Human Sodium Channel Protein Type 11 Subunit Alpha, SCN11A ELISA Kit

SKU: E6728Hu

Size:96 Tests-1 Kit

Background:This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Research_area:Neuroscience

Applications:ELISA

Target_protein:SCN11A

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.16ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Sodium Channel protein type 11 subunit alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UI33

MASS(Da):204,922

GeneID:11280

Synonyms:FEPS3;hNaN;HSAN7;NaN;NAV1.9;Peripheral nerve sodium Channel 5;PN5;SCN11A;Sensory neuron sodium Channel 2;SNS-2;Sodium Channel protein type 11 subunit alpha;Sodium Channel protein type XI subunit alpha;Voltage-gated sodium Channel subunit alpha Nav1.9;

Gene names:SCN11A

Standard solution:2400ng/L