Human Small Nuclear Ribonucleoprotein Sm D1, SNRPD1 ELISA Kit

SKU: E6181Hu

Size:96 Tests-1 Kit

Background:Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA (Probable).

Research_area:Others

Applications:ELISA

Target_protein:SNRPD1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.88ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Small nuclear ribonucleoprotein Sm D1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P62314

MASS(Da):13,282

GeneID:6632

Synonyms:HsT2456;Small nuclear ribonucleoprotein Sm D1;Sm-D autoantigen;SMD1;Sm-D1;snRNP core protein D1;SNRPD;SNRPD1

Gene names:SNRPD1

Standard solution:4800ng/L