Human Serine Threonine-protein Kinase Lmtk3, LMTK3 ELISA Kit

SKU: E6144Hu

Size:96 Tests-1 Kit

Background:Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:LMTK3

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.56ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Serine/threonine-protein kinase LMTK3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96Q04

MASS(Da):153,661

GeneID:114783

Synonyms:Lemur tyrosine kinase 3;LMR3;LMTK3;PPP1R101;Serine/threonine-protein kinase LMTK3;TYKLM3

Gene names:LMTK3

Standard solution:2400ng/L