Human Serglycin, SRGN ELISA Kit

SKU: E4167hu

Size:96 Tests-1 Kit

Background:Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Research_area:Cell Biology

Applications:ELISA

Target_protein:SRGN

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Serglycin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10124

MASS(Da):17,652

GeneID:5552

Synonyms:Hematopoietic proteoglycan core protein;P.PG;Platelet proteoglycan core protein;Secretory granule proteoglycan core protein;Serglycin;SRGN

Gene names:SRGN

Standard solution:48ng/ml