Human Scavenger receptor class B member 1,SRB1 ELISA KIT

SKU: E0351Hu

Size:96 Tests-1 Kit

Background:Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218). {ECO:0000269|PubMed:12016218, ECO:0000269|PubMed:12519372, ECO:0000269|PubMed:16020694, ECO:0000269|PubMed:21226579, ECO:0000269|PubMed:26965621}.; (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed:12356718, PubMed:12913001, PubMed:18000990). Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate (PubMed:12356718). Mediates uptake of M.fortuitum, E.coli and S.aureus (PubMed:16020694). {ECO:0000269|PubMed:12356718, ECO:0000269|PubMed:16020694, ECO:0000269|PubMed:18000990}.

Research_area:

Applications:ELISA

Target_protein:SCARB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:scavenger receptor B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8WTV0

MASS(Da):60878

GeneID:949

Synonyms:SCARB1 CD36L1 CLA1

Gene names:SCARB1

Standard solution:24ng/ml