Human Retinoic Acid Receptor Beta, RARB ELISA Kit

SKU: E6086Hu

Size:96 Tests-1 Kit

Background:Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed: 12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed: 29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:RARB

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.16ng/L

Detection range:5-1000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Retinoic Acid Receptor Beta

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10826

MASS(Da):50,489

GeneID:5915

Synonyms:HBV-activated protein;Nuclear receptor subfamily 1 group B member 2;RARB;RAR-beta;RAR-epsilon;Retinoic acid receptor beta

Gene names:RARB

Standard solution:1280ng/L