Human Ras-related protein Rab-1B,RAB1B ELISA KIT

SKU: E4559Hu

Size:96 Tests-1 Kit

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20545908, PubMed:9437002). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:9437002). Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (PubMed:20545908). Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (By similarity). Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (By similarity). {ECO:0000250|UniProtKB:P10536, ECO:0000269|PubMed:20545908, ECO:0000269|PubMed:9437002}.

Research_area:

Applications:ELISA

Target_protein:RAB1B

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.74ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ras-related protein Rab-1B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H0U4

MASS(Da):22171

GeneID:81876

Synonyms:RAB1B

Gene names:RAB1B

Standard solution:1600ng/L