Human Radiation-inducible Immediate-Early Gene Iex-1, IER3 ELISA Kit

SKU: E6053Hu

Size:96 Tests-1 Kit

Background:May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

Research_area:Cell Biology; Stem Cells

Applications:ELISA

Target_protein:IER3

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.18ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Radiation-inducible immediate-early gene IEX-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P46695

MASS(Da):16,903

GeneID:8870

Synonyms:DIF2;DIF-2;Differentiation-dependent gene 2 protein;GLY96;IER3;IEX1;IEX-1;Immediate early protein GLY96;Immediate early response 3 protein;PACAP-responsive gene 1 protein;PRG1;Protein DIF-2;Protein PRG1;Radiation-inducible immediate-early gene IEX-1

Gene names:IER3

Standard solution:4800ng/L