Human Pro-collagen I alpha 1/COL1A1 ELISA Kit PicoKine®

SKU: EK1692

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: COL1A1

Specificity: Natural and recombinant human COL1A1

Background: Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. And this gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q23-K277 + G1094-L1464

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Uniprot ID: P02452

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1277

Protein Name: Collagen alpha-1

Gene Full Name: collagen type I alpha 1 chain

Synonyms: Alpha 1 type I collagen; COL1A1; Collagen alpha 1(I) chain; collagen; type I; alpha 1; OI4