Human PRELP/Prolargin ELISA Kit PicoKine®

SKU: EK2110

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PRELP

Specificity: Natural and recombinant human PRELP

Background: Prolargin?is a?protein?that in humans is encoded by the?PRELP?gene. It is mapped to 1q32.1. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q21-I382

Clonality:

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Purification:

Reconstitution:

Reference:

Uniprot ID: P51888

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 5549

Protein Name: Prolargin

Gene Full Name: proline and arginine rich end leucine rich repeat protein

Synonyms: Prolargin; Proline-arginine-rich end leucine-rich repeat protein; PRELP; SLRR2A