Human Potassium Voltage-gated Channel Subfamily E Member 1, KCNE1 ELISA Kit

SKU: E4851Hu

Size:96 Tests-1 Kit

Background:Ancillary protein that assembles as a beta subunit with a voltage-gated potassium Channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the Channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium Channel KCNB1 (PubMed: 19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) Channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Research_area:Others

Applications:ELISA

Target_protein:KCNE1

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.55ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Potassium Voltage-Gated Channel Subfamily E Member 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15382

MASS(Da):14,675

GeneID:3753

Synonyms:Delayed rectifier potassium Channel subunit IsK;IKs producing slow voltage-gated potassium Channel subunit beta Mink;KCNE 1;KCNE1;Minimal potassium Channel;Potassium voltage-gated Channel subfamily E member 1

Gene names:KCNE1

Standard solution:4000ng/L