Human PLGF/PGF ELISA Kit PicoKine®

SKU: EK0490

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PGF

Specificity: Natural and recombinant human PLGF

Background: The protein, also called PGF, is 149 amino acids long and shares 53% identity with the platelet-derived growth factor-like region of human VPF. And the N-glycosylated PLGF protein is secreted into the medium and that it functions as a dimer1. The PLGF gene is mapped to 14q24-q31. There are 3 isoforms of PGF, designated PGF1, PGF2, and PGF3. Only PGF2 is able to bind heparin. Additionally, PGF regulates inter- and intramolecular cross-talk between the VEGF receptor tyrosine kinases FLT1 and FLK12. It also can stimulate angiogenesis and collateral growth in ischemic heart and limb with at least a comparable efficiency to VEGF3.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A21-R149

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Reconstitution:

Reference:

Uniprot ID: P49763

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 5228

Protein Name: Placenta growth factor

Gene Full Name: placental growth factor

Synonyms: D12S1900; PGF; PGFL; PIGF; Placenta growth factor; placental growth factor; PLGF; PlGF 2; SHGC 10760