Human Platelet-activating Factor Acetylhydrolase 2, Cytoplasmic, PAFAH2 ELISA Kit

SKU: E2532Hu

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation (PubMed:9494101). Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF (By similarity). Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PAFAH2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Platelet-activating factor acetylhydrolase 2,cytoplasmic

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99487

MASS(Da):44,036

GeneID:5051

Synonyms:HSD-PLA2;PAF:lysophospholipid transacetylase;PAF:sphingosine transacetylase;PAFAH2;Platelet-activating factor acetylhydrolase 2, cytoplasmic;Platelet-activating factor acetyltransferase PAFAH2;SD-PLA2;Serine-dependent phospholipase A2

Gene names:PAFAH2

Standard solution:12.8ng/ml