Human PLA2G4A ELISA Kit PicoKine®

SKU: EK2065

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PLA2G4A

Specificity: Natural and recombinant human PLA2G4A

Background: Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. It is mapped to 1q31.1. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca2+ levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Immunogen: Expression system for standard: NS0; Immunogen sequence: M1-A749

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Reconstitution:

Reference:

Uniprot ID: P47712

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 5321

Protein Name: Cytosolic phospholipase A2

Gene Full Name: phospholipase A2 group IVA

Synonyms: phospholipase A2 group IVA; GURDP; PLA2G4; cPLA2; cPLA2-alpha; PLA2G4A; cPLA2 alpha