Human PILRB ELISA Kit PicoKine®

SKU: EK2256

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PILRB

Specificity: Natural and recombinant human PILRB

Background: Paired immunoglobulin-like type 2 receptor beta is a protein that in humans is encoded by the PILRB gene. The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function.

Immunogen: Expression system for standard: HEK293; Immunogen sequence: Q20-A189

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Reconstitution:

Reference:

Uniprot ID: Q9UKJ0

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 29990

Protein Name: Paired immunoglobulin-like type 2 receptor beta

Gene Full Name: paired immunoglobin like type 2 receptor beta

Synonyms: PILRB; FDFACT; PP1551; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR-beta; Cell surface receptor FDFACT