Human PDGFRA ELISA Kit PicoKine®

SKU: EK2265

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PDGFRA

Specificity: Natural and recombinant human PDGFRA

Background: Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded in the human by the PDGFRA gene. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q24-E524

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Reference:

Uniprot ID: P16234

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 5156

Protein Name: Platelet-derived growth factor receptor alpha

Gene Full Name: platelet derived growth factor receptor alpha

Synonyms: platelet derived growth factor receptor alpha; CD140A; PDGFR-2; PDGFR2; PDGFRA