Human Neuroendocrine Protein 7B2, SCG5 ELISA Kit

SKU: E5755Hu

Size:96 Tests-1 Kit

Background:Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Research_area:Signal Transduction; Neuroscience

Applications:ELISA

Target_protein:SCG5

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.027ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Neuroendocrine protein 7B2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P05408

MASS(Da):23,730

GeneID:6447

Synonyms:7B2;C-terminal Peptide];Neuroendocrine protein 7B2;N-terminal Peptide;P7B2;Pituitary polypeptide;SCG5;Secretogranin V;Secretogranin-5;Secretory granule endocrine protein I;SGNE1;SgV

Gene names:SCG5

Standard solution:24ng/mL