Human Natural Cytotoxicity Triggering Receptor 3, NCR3 ELISA Kit

SKU: E5741Hu

Size:96 Tests-1 Kit

Background:Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Research_area:Others

Applications:ELISA

Target_protein:NCR3

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.47ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Natural Cytotoxicity Triggering Receptor 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O14931

MASS(Da):21,593

GeneID:259197

Synonyms:Activating natural killer receptor p30;CD antigen CD337;Natural cytotoxicity triggering receptor 3;Natural killer cell p30-related protein;NCR 3;NCR3;NKp30;NK-p30

Gene names:NCR3

Standard solution:2400ng/L