Human MyBPC3 ELISA Kit PicoKine®

SKU: EK2324

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MYBPC3

Specificity: Natural and recombinant human MyBPC3

Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

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Uniprot ID: Q14896

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4607

Protein Name: Myosin-binding protein C, cardiac-type

Gene Full Name: myosin binding protein C3

Synonyms: Cardiac MyBP C; CMH4; FHC; MYBP C; MYBPC3