Human Multidrug resistance protein 1,ABCB1 ELISA KIT

SKU: E4736Hu

Size:96 Tests-1 Kit

Background:Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218). {ECO:0000269|PubMed:2897240, ECO:0000269|PubMed:8898203, ECO:0000269|PubMed:9038218}.

Research_area:

Applications:ELISA

Target_protein:ABCB1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.15ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Multidrug resistance protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08183

MASS(Da):141479

GeneID:5243

Synonyms:ABCB1 MDR1 PGY1

Gene names:ABCB1

Standard solution:3200ng/L