Human Mucin-1, MUC1 ELISA Kit

SKU: E1939Hu

Size:96 Tests-1 Kit

Background:The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Research_area:Cancer

Applications:ELISA

Target_protein:MUC1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Mucin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15941

MASS(Da):122,102

GeneID:4582

Synonyms:Breast carcinoma-associated antigen DF3;CA 15-3;Cancer antigen 15-3;Carcinoma-associated mucin;CD antigen CD227;EMA;Episialin;H23AG;KL-6;Krebs von den Lungen-6;MUC 1;MUC1;MUC-1;MUC1-alpha;MUC1-beta;MUC1-CT;MUC1-NT;Mucin-1;Mucin-1 subunit alpha;Mucin-1 subunit beta;Peanut-reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor-associated epithelial membrane antigen;Tumor-associated mucin

Gene names:MUC1

Standard solution:16ng/ml