Human Monocarboxylate Transporter-1,SLC16A1 ELISA KIT

SKU: E4648Hu

Size:96 Tests-1 Kit

Background:Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. {ECO:0000269|PubMed:17701893}.

Research_area:

Applications:ELISA

Target_protein:SLC16A1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Monocarboxylate Transporter-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P53985

MASS(Da):53944

GeneID:6566

Synonyms:SLC16A1 MCT1

Gene names:SLC16A1

Standard solution:24ng/ml