Human MMP-1 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0458

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MMP1

Specificity: Natural and recombinant human total MMP-1

Background: Matrix metalloproteinase-1 (MMP-1) is also known as collagenase. Matrix metalloproteinases (MMPs) are zinc-dependent proteases that degrade extrMMP-1llular matrix proteins. The MMPs comprise a family of at least 20 proteolytic enzymes that play an essential role in tissue remodeling. Matrix metalloproteinase-1 (MMP-1) plays an important role in the degradation of collagen in inflammatory diseases. MMP1 (interstitial collagenase), MMP9 (gelatinase B) and MMP12 (macrophage elastase) are thought to be important in the development of emphysema. Smoking-induced MMP-1 might be important in the skin-ageing effects of tobacco smoking. The standard product used in this kit is human MMP-1 with the molecular mass of 51-53KDa. The detected MMP-1 includes zymogen and active enzyme.

Immunogen: Expression system for standard: NS0; Immunogen sequence: F20-N469

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Reference:

Uniprot ID: B4DN15

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4312

Protein Name: interstitial collagenase

Gene Full Name: matrix metallopeptidase 1

Synonyms: CLG; CLGN; Fibroblast collagenase; Interstitial collagenase; Matrix metalloproteinase 1; MMP 1; MMP1