Human Microtubule Associated Protein RP/EB Family Member 1, MAPRE1 ELISA Kit

SKU: E2946Hu

Size:96 Tests-1 Kit

Background:Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton (PubMed:12388762, PubMed:16109370, PubMed:19632184, PubMed:21646404, PubMed:28726242, PubMed:28814570). Promotes cytoplasmic microtubule nucleation and elongation (PubMed:12388762, PubMed:16109370, PubMed:19632184, PubMed:21646404, PubMed:28726242, PubMed:28814570). May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (PubMed:12388762). Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:28814570). Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570). Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (PubMed:28726242). May play a role in cell migration (By similarity).

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:MAPRE1

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.71ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Microtubule associated protein RP/EB family member 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15691

MASS(Da):29,999

GeneID:22919

Synonyms:APC-binding protein EB1;EB1;End-binding protein 1;MAPRE1;Microtubule-associated protein RP/EB family member 1

Gene names:MAPRE1

Standard solution:3200ng/L