Human Lipocalin-2/NGAL PicoKine® Quick ELISA Kit

SKU: FEK0853

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CST3

Specificity: Natural and recombinant Human LCN2

Background: Lipocalin-2 (LCN2), also known as NGAL, is a protein associated with neutrophil gelatinase.1 The LCN2 gene is located at 9q34 and contains 7 exons.2 The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. NGAL tightly binds bacterial catecholate-type ferric siderophores through a cyclically permuted, hybrid electrostatic/cation-pi interaction and is a potent bacteriostatic agent in iron-limiting conditions.3 The primary LCN2 transcript is 3,696 nucleotides long, and the processed transcript is 809 nucleotides long.4 LCN2 expression in adult bone marrow, uterus, prostate, salivary gland, stomach, appendix, colon, trachea, and lung, and in fetal spleen and lung.The standard product used in this kit is recombinant human NGAL, consisting of 178 amino acids with the molecular mass of 22KDa.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q21-G198

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Reference:

Uniprot ID: P80188

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3934

Protein Name: Neutrophil gelatinase-associated lipocalin

Gene Full Name: lipocalin 2

Synonyms: lipocalin 2; 24p3; MSFI; NGAL; p25; LCN2