Human Leukocyte Common Antigen, LCAELISA Kit

SKU: E0285Hu

Size:96 Tests-1 Kit

Background:Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.

Research_area:Others

Applications:ELISA

Target_protein:LCA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:leukocyte common antigen

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08575

MASS(Da):147,486

GeneID:5788

Synonyms:B220;CD antigen CD45;CD45;GP180;LCA;L-CA;Leukocyte common antigen;LY5;Receptor-type tyrosine-protein phosphatase C;T200

Gene names:PTPRC

Standard solution:80ng/ml