Human LAP(TGF-Beta1) ELISA Kit PicoKine®

SKU: EK1218

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TGFB1

Specificity: Natural and recombinant human LAP(TGF-beta1)

Background: TGFbeta1 is secreted as a latent form, which consists of its mature form and a latency-associated peptide (beta1-LAP) in either the presence or the absence of additional latent TGF-beta1-binding protein. Processing and cleavage of the precursor protein between amino acids 278 and 279 results in the formation of LAP dimers and TGF beta dimers that then non-covalently associate with each other to form the small latent TGF beta complex. LAP is secreted and can be found in the extracellular matrix. In addition, LAP can also be expressed on platelets and activated regulatory T cells.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L30-R278

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Reference:

Uniprot ID: P01137

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 7040

Protein Name: Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

Gene Full Name: transforming growth factor beta 1

Synonyms: CED; DPD1; LAP; TGF beta 1; tgf beta1; TGFB; TGFB1; TGFbeta; TGF-beta 1; tgfbeta1; tgf-beta1; TGFβ; TGF-β; TGFβ1; TGF-β1