Human L-dopachrome tautomerase,MIF ELISA KIT

SKU: E5558Hu

Size:96 Tests-1 Kit

Background:Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. {ECO:0000269|PubMed:15908412, ECO:0000269|PubMed:17443469, ECO:0000269|PubMed:23776208}.

Research_area:

Applications:ELISA

Target_protein:MIF

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.02ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:L-dopachrome tautomerase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P14174

MASS(Da):12476

GeneID:4282

Synonyms:MIF GLIF MMIF

Gene names:MIF

Standard solution:3200ng/L