Human Interleukin 29, IL-29 ELISA Kit

SKU: E0040Hu

Size:96 Tests-1 Kit

Background:Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Research_area:Immunology

Applications:ELISA

Target_protein:IL29

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.42ng/L

Detection range:6-1800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 29

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8IU54

MASS(Da):21,898

GeneID:282618

Synonyms:Cytokine Zcyto21;IFN-lambda-1;IL 29;IL29;IL-29;Interferon lambda-1;Interleukin-29

Gene names:IL29

Standard solution:1920ng/L