Human Interleukin 18, IL-18 ELISA Kit

SKU: E0147Hu

Size:96 Tests-1 Kit

Background:A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed: 14528293, PubMed: 25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed: 10653850).

Research_area:Immunology

Applications:ELISA

Target_protein:IL18

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.2ng/L

Detection range:0.5-100ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 18

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14116

MASS(Da):22,326

GeneID:3606

Synonyms:Iboctadekin;IFN-gamma-inducing factor;IL 18;IL-1 gamma;IL18;IL-18;Interferon gamma-inducing factor;Interleukin-1 gamma;Interleukin-18;

Gene names:IL18

Standard solution:128ng/L