Human Integrin Beta-8, ITGB8 ELISA Kit

SKU: E5487Hu

Size:96 Tests-1 Kit

Background:Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (PubMed: 1918072). It recognizes the sequence R-G-D in its ligands (PubMed: 1918072). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated Peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (Probable). Required during vasculogenesis (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ITGB8

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.053ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Integrin Beta-8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P26012

MASS(Da):85,632

GeneID:3696

Synonyms:Integrin beta-8;ITGB 8;ITGB8

Gene names:ITGB8

Standard solution:48ng/ml