Human Integrin alpha 2b,ITGA2B;CD41 ELISA KIT

SKU: E3934Hu

Size:96 Tests-1 Kit

Background:Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Research_area:

Applications:ELISA

Target_protein:ITGA2B

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Integrin alpha 2b

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08514

MASS(Da):113377

GeneID:3674

Synonyms:ITGA2B GP2B ITGAB

Gene names:ITGA2B

Standard solution:24ng/ml