Human IL7R/CD127 ELISA Kit PicoKine®

SKU: EK0713

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL7R

Specificity: Natural and recombinant human IL7R

Background: The interleukin-7 receptor (IL7R) is a protein found on the surface of cells. It is mapped to 5p13.2. The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. IL7R has been shown to play a critical role in the development of immune cells called lymphocytes-specifically in a process known as V (D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. What's more, IL7R antagonism is efficacious in treatment of EAE through its effects on Th17 cells and is a potential treatment for MS.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E21-I262

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P16871

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 3575

Protein Name: Interleukin-7 receptor subunit alpha

Gene Full Name: interleukin 7 receptor

Synonyms: CD127; CDW127; IL 7 receptor subunit alpha; IL 7R alpha; IL 7R subunit alpha; IL 7RA; IL7R; IL-7R; IL 7R; IL7RA; ILRA; interleukin 7 receptor