Human IL1R2/Il 1 Rii ELISA Kit PicoKine®

SKU: EK0396

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL1R2

Specificity: Natural and recombinant human IL1R2

Background: Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin-1 receptor family. It is mapped to 2q11.2. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. The secreted IL1R2 recruits secreted IL1RAP with high affinity, and this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Immunogen: Expression system for standard: NS0; Immunogen sequence: F14-E343

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Uniprot ID: P27930

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 7850

Protein Name: Interleukin-1 receptor type 2

Gene Full Name: interleukin 1 receptor type 2

Synonyms: CD121b; CDw121b; IL 1R 2; IL 1R beta; IL 1RT 2; IL 1RT2; IL1 Receptor 2; IL-1 Receptor 2; IL1 Receptor II; IL-1 Receptor II; IL1R2; IL-1R2; IL1RB; IL-1RII; Interleukin 1 receptor beta; Interleukin 1 receptor type 2; Interleukin 1 receptor type II