Human IL15RA ELISA Kit PicoKine®

SKU: EK1663

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL15RA

Specificity: Natural and recombinant human IL15RA

Background: Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor which is encoded by the gene IL15RA in humans. The human IL15RA gene was mapped to chromosome 10p15-p14 by FISH and the mouse Il15ra gene was mapped to chromosome 2. The cytoplasmic domain of IL15R-alpha, like that of IL2R-alpha, was dispensable for mitogenic signaling, suggesting that the primary role of the alpha chains is to confer high-affinity binding. At high concentrations, IL15, like IL2, was able to signal through a complex of IL2R-beta and -gamma in the absence of the alpha subunit. The soluble receptor displayed high affinity for IL15 and inhibited both binding of IL15 to the membrane receptor and IL15-induced cell proliferation.

Immunogen: Expression system for standard: NS0; Immunogen sequence: I31-T172

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Reference:

Uniprot ID: Q13261

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3601

Protein Name: Interleukin-15 receptor subunit alpha

Gene Full Name: interleukin 15 receptor subunit alpha

Synonyms: IL 15 receptor subunit alpha; IL 15R alpha; IL 15RA; IL15RA; IL-15RA; interleukin 15 receptor; alpha; sIL 15 receptor subunit alpha; sIL 15R alpha; sIL 15RA