Human IL-8/Interleukin-8/CXCL8 ELISA Kit PicoKine®

SKU: EK0413

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CXCL8

Specificity: Natural and recombinant human IL-8

Background: Interleukin-8, also called neutrophil-activating peptide-1 or SCYB8, is a tissue-derived peptide secreted by several types of cells in response to inflammatory stimuli. Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8, suggested gene symbol IL8) is a cytokine that chemoattracts and activates neutrophils. IL-8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL-8 from adipose tissue could be involved in some of the obesity-related complications. The MDNCF/IL-8 gene is placed on the human gene map at position 4q12-q21. This is the same location where at least three other members (platelet factor 4, melanoma growth stimulatory activity, and interferon-gamma induced factor) of the platelet factor 4 gene superfamily reside. Human IL-8 consists of 99 amino acids in precursor form and 79 amino acids in mature form.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S28-S99

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Uniprot ID: P10145

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3576

Protein Name: Interleukin-8

Gene Full Name: C-X-C motif chemokine ligand 8

Synonyms: C X C motif chemokine 8; CXCL8; CXCL8; IL8; CXCL8/IL-8; Emoctakin; GCP 1; GCP1; IL 8; IL 8(1 77); IL8; IL-8; IL8/NAP1 form I Interleukin 8; IL8/NAP1 form II; IL8/NAP1 form VI; interleukin 8; MDNCF; MDNCF b IL 8(5 77) IL 8(6 77); NAF; NAF IL 8(7 77); NAP 1; NAP1; Neutrophil activating factor; Protein 3 10C