Human IL-18BP ELISA Kit PicoKine®

SKU: EK1282

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL18BP

Specificity: Natural and recombinant human IL-18BP

Background: Interleukin-18-binding protein, also known as IL18BPa, is a protein that in humans is encoded by the IL18BP gene. It is mapped to 11q13.4. The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. It has been found that IL18BP expression in intestinal tissue is increased in endothelial cells as well as cells of the submucosa and overlying lymphoid aggregates in Crohn disease.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T31-G194

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Reference:

Uniprot ID: O95998

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 10068

Protein Name: Interleukin-18-binding protein

Gene Full Name: interleukin 18 binding protein

Synonyms: IL 18BP; IL18BP; IL-18BP; IL18BPa; interleukin 18 binding protein; Tadekinig alfa