Human IL-16 ELISA Kit PicoKine®

SKU: EK0428

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL16

Specificity: Natural and recombinant human IL-16

Background: Interleukin 16 (IL-16) is a cytokine that released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. By Southern blot analysis and PCR using a human/rodent somatic cell hybrid mapping panel, The human IL16 is encoded by a single-copy gene on chromosome 15. Using a combination of STS-content mapping, radiation-hybrid mapping, and genetic mapping, it was refined the assignment to 15q26.1. The mouse Il16 gene was mapped to chromosome 7 in a region showing homology of synteny to human 15q26.1. IL-16 was originally described as a factor that could attract activated T cells in humans, it was previously called lymphocyte chemoattractant factor (LCF), and the augmentation of IL16stimulation by CCR5 plays a role in regulation of Th1 cell recruitment and activation at sites of inflammation.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: P1204-S1332

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Reference:

Uniprot ID: Q14005

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3603

Protein Name: Pro-interleukin-16 [Cleaved into: Interleukin-16

Gene Full Name: interleukin 16

Synonyms: HsT19289; IL 16; IL16; IL-16; LCF; prIL 16; Pro interleukin 16