Human IL-1 RL1 / ST2 PicoKine® Quick ELISA Kit

SKU: FEK1116

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL1RL1

Specificity: Natural and recombinant human IL1RL1 as well as free IL1RL1 and IL-33 complexed IL1RL1.

Background: Interleukin 1 receptor-like 1, also known as IL1RL1 or ST2, is a protein that in humans is encoded by the IL1RL1 gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. TL1RL1 is necessary for endotoxin tolerance and, by inhibiting TLR responses, enhances Th2 responses. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Immunogen: Expression system for standard: NS0; Immunogen sequence: K19-S328

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Uniprot ID: Q01638

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 9173

Protein Name: Interleukin-1 receptor-like 1

Gene Full Name: interleukin 1 receptor like 1

Synonyms: DER4; FIT 1; IL1RL1; IL-1RL1; IL-33R; interleukin 1 receptor like 1; Protein ST2; ST2; ST2L; ST2V; T1; IL 1RL1