Human IL-1 Alpha/IL-1F1/IL1A PicoKine&reg Quick ELISA Kit

SKU: FEK0389

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL1A

Specificity: Natural and recombinant human IL-1 alpha

Background: Interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are two biochemically distinct, but distantly related, polypeptidic cytokines that play a key role in inflammation, immunologic reactions, and tissue repair. IL-1 alpha has been implicated in the pathogenesis of infectious, autoimmune and inflammatory diseases. Recently, it has been shown that IL-1 alpha is identical to hematopoietin 1, which is described as a hematopoietic growth factor acting on early progenitor cells in synergy with other hematopoietic growth factors. The human interleukin 1 alpha gene is assigned to chromosome 2. Genetic polymorphisms at interleukin (IL)-1alpha and IL-1beta have been recently suggested to be associated with severity of adult periodontitis. The murine IL-1 alpha and IL-1 beta genes encode structurally and evolutionarily related cytokines that exert a regulatory role in numerous physiological processes including hemopoiesis. The standard product used in this kit is recombinant human IL-1alpha with the molecular mass of 18kDa.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S113-A271

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Reference:

Uniprot ID: P01583

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3552

Protein Name: Interleukin-1 alpha

Gene Full Name: interleukin 1 alpha

Synonyms: Hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL-1; IL1 ALPHA; IL-1 alpha; IL1A; IL1F1; IL-1α; Interleukin 1 alpha; interleukin 1, alpha; IL-1A