Human IGFBP4 PicoKine® ELISA Kit

SKU: EK0388

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IGFBP4

Specificity: Natural and recombinant human IGFBP4

Background: Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4gene. This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. In addition, IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. It is secreted by all colon cancer cells.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D22-E258

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Reference:

Uniprot ID: P22692

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3487

Protein Name: Insulin-like growth factor-binding protein 4

Gene Full Name: insulin like growth factor binding protein 4

Synonyms: BP 4; HT29 IGFBP; IBP 4; IBP4; IGF binding protein 4; IGFBP 4; IGFBP4