Human IGF1R/Igf1 Receptor ELISA Kit PicoKine®

SKU: EK0776

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IGF1R

Specificity: Natural and recombinant human IGF1R

Background: IGF1R, also called IGFR or insulin-like growth factor 1 receptor, is a protein that found on the surface of human cells. This gene is mapped to 15q26.3. IGF1R belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. IGF1R also plays a critical role in transformation events. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E31-N932

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Reference:

Uniprot ID: P08069

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3480

Protein Name: Insulin-like growth factor 1 receptor

Gene Full Name: insulin like growth factor 1 receptor

Synonyms: CD221; IGF I receptor; IGF1R; IGFIR; IGFR; JTK13