Human Histone Deacetylase 9, HDAC9 ELISA Kit

SKU: E5411Hu

Size:96 Tests-1 Kit

Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:HDAC9

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.044ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Histone Deacetylase 9

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UKV0

MASS(Da):111,297

GeneID:9734

Synonyms:HD7;HD7b;HD9;HDAC 9;HDAC9;Histone deacetylase 7B;Histone deacetylase 9;Histone deacetylase-related protein;MEF2-interacting transcription repressor MITR;

Gene names:HDAC9

Standard solution:25.6ng/mL