Human Granzyme B ELISA Kit PicoKine®

SKU: EK1114

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: GZMB

Specificity: Natural and recombinant human Granzyme B

Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Immunogen: Expression system for standard: NS0; Immunogen sequence: I21-Y247

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Reference:

Uniprot ID: P10144

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3002

Protein Name: Granzyme B

Gene Full Name: granzyme B

Synonyms: CCPI; CGL 1; CGL1; CSP B; CSPB; CTLA1; CTSGL1; Endogenous granzyme B; Granzyme B; GZMB; HLP; SECT