Human Gastrotropin, FABP6 ELISA Kit

SKU: E5323Hu

Size:96 Tests-1 Kit

Background:Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). [Isoform 2]: Essential for the survival of colon cancer cells to bile acid-induced apoptosis.

Research_area:Signal Transduction; Cancer; Metabolism; Cardiovascular

Applications:ELISA

Target_protein:FABP6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.048ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Gastrotropin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P51161

MASS(Da):14,371

GeneID:2172

Synonyms:FABP 6;FABP6;Fatty acid-binding protein 6;Gastrotropin;GT;I-15P;I-BABP;ILBP;Ileal lipid-binding protein;Intestinal 15 kDa protein;Intestinal bile acid-binding protein

Gene names:FABP6

Standard solution:48ng/ml