Human Frizzled-9, FZD9 ELISA Kit

SKU: E2366Hu

Size:96 Tests-1 Kit

Background:Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (By similarity). May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (PubMed:27509850). During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:FZD9

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.87ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Frizzled-9

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00144

MASS(Da):64,466

GeneID:8326

Synonyms:CD antigen CD349;CD349;Frizzled-9;Fz-9;FZD3;FZD9;FzE6;hFz9

Gene names:FZD9

Standard solution:6400ng/L