Human Frizzled-10, FZD10 ELISA Kit

SKU: E2365Hu

Size:96 Tests-1 Kit

Background:Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:FZD10

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.14ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Frizzled-10

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9ULW2

MASS(Da):65,336

GeneID:11211

Synonyms:CD antigen CD350;CD350;Frizzled-10;Fz10;FZ-10;FZD10;FzE7;hFz10

Gene names:FZD10

Standard solution:3200ng/L