Human FOLR1/Alpha Fr ELISA Kit PicoKine®

SKU: EK1242

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FOLR1

Specificity: Natural and recombinant human FOLR1

Background: Folate receptor 1 adult is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member of the folate receptor (FOLR) family. It is mapped to 11q13.4. FOLR1 expression in Jurkat cells facilitated MBG or EBO entry, and FR-blocking reagents inhibited infection of MBG or EBO. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. The FOLR1 gene encodes the adult folate receptor, or folate-binding protein (FBP), which has a high affinity for folic acid and for several reduced folic acid derivatives, and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is also an important regulator of milk protein synthesis.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: R25-S234

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Reference:

Uniprot ID: P15328

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2348

Protein Name: Folate receptor alpha

Gene Full Name: folate receptor alpha

Synonyms: Adult folate binding protein; FBP; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor; adult; FOLR; FOLR1; FR alpha; KB cells FBP; MOv18