Human Ficolin-3 PicoKine® Quick ELISA Kit

SKU: FEK1259

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FCN3

Specificity: Natural and recombinant human Ficolin-3

Background: Ficolin-3, also known as HAKA1, is a protein that in humans is encoded by the FCN3 gene. It is mapped to 1p36.11. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Ficolin-3 is expressed as a 35-kD protein that reacts with systemic lupus erythematosus sera. Ficolin-3 does not bind fibronectin (FN1), elastin (ELN), or zymosan, and the lectin activity of the Ficolin-3 is calcium independent. Homozygosity for the variant in the FCN3 gene results in a recessive complement deficiency syndrome.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q24-R299

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Reference:

Uniprot ID: O75636

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8547

Protein Name: Ficolin-3

Gene Full Name: ficolin 3

Synonyms: ficolin 3; FCN3; FCNH; Ficolin 3; Ficolin-3; HAKA1; Hakata antigen