Human Eukaryotic translation initiation factor 5A-1,EIF5A ELISA KIT

SKU: E7267Hu

Size:96 Tests-1 Kit

Background:mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts. {ECO:0000269|PubMed:15371445, ECO:0000269|PubMed:15452064, ECO:0000269|PubMed:16987817, ECO:0000269|PubMed:17187778, ECO:0000269|PubMed:17360499}.

Research_area:

Applications:ELISA

Target_protein:EIF5A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.091ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Eukaryotic translation initiation factor 5A-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P63241

MASS(Da):16832

GeneID:1984

Synonyms:EIF5A

Gene names:EIF5A

Standard solution:64ng/ml